Chemistry Letters, Vol.33, No.7, 918-919, 2004
Total synthesis of (-)-ent-jolkinolide D
The first total synthesis of the enantiomer of jolkinolide D, a bioactive diterpene from Euphorbia jolkini Boiss, was achieved from abietic acid. The enantiomer did not exhibit the biological activities that the natural jolkinolide D possesses.