Chemistry Letters, Vol.33, No.12, 1626-1627, 2004
TTMPP catalyzed one-pot silyl ketene acetal-imine condensation route to beta-lactams
Highly nucleophilic phosphine, tris(2,4,6-trimethoxy phenyl) phosphine (TTMPP) catalyzes a unique one-pot cyclization reaction between silyl ketene acetal and aldimine, resulting in beta-lactam.