Journal of Molecular Catalysis A-Chemical, Vol.193, No.1-2, 89-95, 2003
Remote substituent effect in palladium/pyridinyl-oxazolines catalyzed asymmetric allylic alkylation
The chiral ligands containing pyridinyl moieties and oxazolines bridged by disubstituted methylene 2-4 were prepared and they provided ee values 17-68% higher than unsubstituted analogues 1 in the palladium-catalyzed enantioselective allylic alkylation of 1,3-diphenyl-2-propenyl acetate with dimethyl malonate. (C) 2002 Elsevier Science B.V. All rights reserved.