Journal of Molecular Catalysis A-Chemical, Vol.242, No.1-2, 57-61, 2005
Asymmetric reduction of prochiral ketones with borane using chiral squaric amino alcohols derived from camphor as catalysts
A series of new chiral squaric amino alcohols derived from (R)-(+)-camphor and squaric acid were synthesized, and applied to the enantioselective reduction of prochiral ketones with borane to give secondary alcohols with excellent enantiomeric excesses (up to 99%). (c) 2005 Elsevier B.V. All rights reserved.