Journal of Molecular Catalysis A-Chemical, Vol.244, No.1-2, 118-123, 2006
Dendritic BIPHEP: Synthesis and application in asymmetric hydrogenation of beta-ketoesters
A series of new chiral dendritic BIPHEP ligands have been prepared and their applications in the Ru-catalyzed asymmetric hydrogenation of beta-ketoesters were investigated. Ruthenium catalysts containing these dendrimer ligands were effective in the hydrogenation of beta-ketoesters. It was found that the size of the dendritic wedges influenced the enantioselectivity significantly. (c) 2005 Elsevier B.V. All rights reserved.