Regioselective nucleophilic opening of epoxides and aziridines under neutral conditions in the presence of beta-cyclodextrin in water

Srinivas B; Kumar VP; Sridhar R; Surendra K; Nageswar YVD; Rao KR

Journal of Molecular Catalysis A-Chemical, Vol.261, No.1, 1-5, 2007

DOI10.1016/j.molcata.2006.07.040 Export Citation

Regioselective nucleophilic opening of epoxides and aziridines under neutral conditions in the presence of beta-cyclodextrin in water

Srinivas B, Kumar VP, Sridhar R, Surendra K, Nageswar YVD, Rao KR

A variety of beta-hydroxy nitriles and beta-amino alcohols have been synthesized by the regioselective ring opening of epoxides and aziridines under neutral and aqueous conditions in the presence of beta-cyclodextrin in good yields. (c) 2006 Elsevier B.V. All rights reserved.

Keywords:epoxide;sodium cyanide;beta-hydroxy nitrile;N-tosyl aziridines;beta-amino alcohols;beta-cyclodextrin;supramolecular catalysis water