Journal of Molecular Catalysis A-Chemical, Vol.261, No.1, 120-124, 2007
The application of chiral, non-racemic N-alkylephedrine and N,N-dialkylnorephedrine as ligands for the enantioselective aryl transfer reaction to aldehydes
The catalytic enantioselective arylation of several aldehydes using arylboronic acids as the source of transferable aryl groups is described; the reaction is found to proceed in excellent yields and high enantioselectivities (up to 96% ee) in the presence of a chiral amino alcohol derived from ephedrines and congeners. (c) 2006 Elsevier B.V All rights reserved.