A theoretical analysis of the effects of Row and mixing on the operating features of a stirred column reactor(SCR) with multistage mixers and cooling partition plates was conducted. A method for calculating the concentration reduction for a second order chemical reaction in a SCR was proposed. The reactants concerned were pre-mixed before feeding into the SCR. The SCR was composed of a number of stages with interstage backmixing. Experimental investigation with various reaction media were carried out in order to study the effect of mixing on the operational performance of the SCR. The experimental data were compared with the theoretical results.