The ignition and the oxidation of tetrahydropyran have been studied in a single-pulse shock tube under reflected shock wave conditions, and also in a high-pressurejet-stirred reactor (JSR). These experiments cover a wide range of conditions: 2-10 atm, 0.5 less than or equal to phi less than or equal to 2.0, 800-1700 K. The ignition delays of tetrahydropyran measured in a shock tube have been used to propose an overall representation for the dependence of ignition delay time on the concentrations of each component in the ignitable gas mixture: tau(all) = 10-(13.6) exp (15360/T-5) [C5H10O](0.0026) [O-2](-0.868) [Ar](0.0274) (units: s, mole/dm(3), K). Concentration profiles of the reactants, stable intermediates and products of the oxidation of tetrahydropyran were measured in a JSR. A numerical model, consisting of a detailed kinetic reaction mechanism with 507 reactions (most of them reversible) of 72 species describes the ignition of tetrahydropyran in reflected shock waves and its oxidation in a jetstirred reactor. A fairly good agreement between the experimental results and the model was observed. Detailed kinetic modeling identified the major reaction paths.