In this paper. a fuzzy heuristic approach based on the fuzzification of two heuristic rules is presented for synthesizing sharp multicomponent separation sequences. The proposed procedure combines the values of the estimate separation mass load coefficients and the difference in normal boiling points of the components in a fuzzy rule based procedure. This approach is illustrated with several examples with 4, 5, 7 and 8-component mixtures to be separated and its efficiency is compared with methods taken from literature.