Spherical-particle assemblies (see Figure) are fabricated by micropatterning of methanol droplets containing SiO2. Hydrophilic regions of a patterned self-assembled monolayer (SAM) are covered with methanol solution containing SiO2 Particles and immersed in decahydronaphthalene. The particles assemble to form. micropatterns of spherical-particle assemblies on the hydrophilic regions of the SAM.