화학공학소재연구정보센터
Biochemical and Biophysical Research Communications, Vol.324, No.2, 547-553, 2004
In silico identification and structural features of six new genes similar to MATER specifically expressed in the oocyte
In the present work. we have used the in silico subtraction methodology to identify six new mouse genes similar to NALP5/ MATER, whose ESTs were represented almost exclusively in egg libraries. Five genes were selected for RT-PCR and/or in situ hybridization. These experiments confirmed their oocyte restricted expression. Five of these genes are localized on mouse chromosome 7, as is NALP5/MATER, among them, three are localized in a 300 kb cluster. (C) 2004 Elsevier Inc. All rights reserved.