Chemical modification of chitosan: Preparation and lectin binding properties of alpha-galactosyl-chitosan conjugates. Potential inhibitors in acute rejection following xenotransplantation

Sashiwa H; Thompson JM; Das SK; Shigemasa Y; Tripathy S; Roy R

Biomacromolecules, Vol.1, No.3, 303-305, 2000

Sashiwa H, Thompson JM, Das SK, Shigemasa Y, Tripathy S, Roy R

Water-soluble alpha -galactosyl-chitosan conjugates were prepared by reductive amination of p-formylphenyl beta -melibioside on chitosan in good yield. Strong binding with phytohemagglutinin was demonstrated using Griffonia simplicifolia.