Advanced Functional Materials, Vol.17, No.5, 718-729, 2007
Rate acceleration of light-driven rotary molecular motors
One of the key challenges in taking light-driven unidirectional rotary motors from discovery to application is to increase the rate of rotation. Herein, we review our ongoing efforts to address this issue by meticulous improvement to the molecular design. To accelerate the rotary cycle, we have focused primarily on the rate-limiting thermal isomerization step. This has been a fascinating and formidable objective, given that the first system we reported had a half-life of over one week at room temperature! Our research has ultimately led to the construction of a unidirectional rotary molecular motor with a cycle 108 times faster than the original; that is, it can in principle function at 44 rotations per second.