Poly(lactic acid-co-aspartic acid) was obtained by copolymerizing DL-lactic acid and L-aspartic acid. The structure of poly(lactic acid-co-aspartic acid) was characterized by IR, H-1 NMR. The characters of poly(lactic acid-co-aspartic acid) were determined by hydrolytic degradable experiments, which indicate that the degradation rate of poly(lactic acid-co-aspartic acid) was accelerated by aspartic acid synthesized in the polymers. (c) 2005 Elsevier B.V. All rights reserved.