Closure laws are needed for the qualification of CFD codes for two-phase flows. In case of bubbly and slug flow, forces acting on the bubbles usually model the momentum transfer between the phases. Several models for such forces can be found in Literature. They show, that these forces depend on the liquid flow field as well as on the size and the shape of the bubbles. A validation of consistent sets of bubble force models for poly-disperse flows is given, basing on a detailed experimental database for vertical pipe flows, which contains data on the radial distribution of bubbles of different size as well as local bubble size distributions. A one-dimensional (ID) solver provides velocity profiles and bubble distributions in radial direction. It considers a large number of bubble size classes and is used for the comparison with the experiments. The simplified model was checked against the results of full 3D simulations done by the commercial code CFX-5.7 for simplified monodisperse cases. The effects of the number of bubbles classes as well as the effect of the lateral extension of the bubbles were analyzed. For the validation of bubble force models measured bubble size distributions were taken as an input for the calculation. On basis of the assumption of an equilibrium of the lateral bubble forces, radial volume fraction profiles were calculated separately for each bubble class. In the result of the validation of different models for the bubble forces, a set of Tomiyama lift and wall force, deformation force and Favre averaged turbulent dispersion force was found to provide the best agreement with the experimental data. Some discrepancies remain at high liquid superficial velocities. (c) 2007 Elsevier Ltd. All rights reserved.