Bisphenol A (BPA) imprinted polyethersulforie (PES) particles were prepared for the recognition of BPA by means of phase inversion method. During the preparation of the BPA-imprinted particles, acetone, ethanol and acetone/ethanol solutions were used to extract the template BPA molecules. The SEM morphology and the recognition experiments suggested that the acetone/ethanol provided an efficient way to extract the BPA from the imprinted PES particles. The binding and recognition ability for the imprinted particles disappeared under alkali condition, and they recovered as soon as possible when the solution changed from alkali condition to neutral or acid condition. With the addition of Na+, Mg2+, and Cl-, the binding amounts for the imprinted particles and non-imprinted particles were not changed heavily, which suggested the potential application of the particles in seawater. In the BPA/BPA analog-Lie mixed solution, the imprinted particles showed selectivity for the template molecules BPA. The FTIR results suggested that the PES and BPA interacted through hydrogen bonds. (c) 2007 Wiley Periodicals, Inc.