The thermodynamic properties of 2-pyridinealdoxime were investigated through the thermogravimetric (TG) analysis and differential scanning calorimetry (DSC). Low-temperature heat capacity C-p.m of 2-pyridinealdoxime (C6H6N2O; CAS 873-69-8) was measured in the temperature range from (80 to 373) K with a high precision automated adiabatic calorimeter. No phase transition or thermal anomaly was observed in this range. The thermodynamic functions [H-T - H-298.15] and [S-T - S-298.15] were calculated in the range from (80 to 375) K. The constant-volume energy and standard molar enthalpy of combustion have been determined Delta U-c (C6H6N2O, cr) = Delta H-f degrees(m) (C6H6N2O, cr) = - (3297.11 +/- 1.53) kJ center dot mol(-1) (based on Delta n being zero in reaction of the combustion), by means of a precision oxygen-bomb combustion calorimeter at T= (298.15 +/- 0.001) K. The standard molar enthalpy of formation has been derived, Delta H-f degrees(m) (C6H6N2O, cr) = (78.56 +/- 2.43) kJ center dot mol(-1), from the standard molar enthalpy of combustion in combination with other auxiliary thermodynamic quantities through a Hess thermochemical cycle. (C) 2006 Elsevier Ltd. All rights reserved.