This work presents the modeling and the selection of best topology of gas-solid-solid reactor for direct synthesis of methanol from methane. A gas-solid-solid system is used for such a purpose consisting of a catalyst fixed bed and a second solid that flow in counter-current with the flowing gas. A selective adsorption system enables the intensification of the partial oxidation of methane increasing more than 12 times the methanol production. The solution of the mass, energy and momentum transfer equations for a gas-solid-solid catalytic system was developed with Fortran and the NAG mathematical libraries. (c) 2007 Elsevier B.V. All rights reserved.