Chemistry Letters, Vol.36, No.8, 996-997, 2007
N,N'-dichlorobis(2,4,6-trichlorophenyl)urea (CC-2): An efficient reagent for N-chlorination of amino esters, amide, and peptides
A simple, efficient, and rapid protocol for N-chlorination of various protected amino esters, amides, and peptides has been described. N,N'-dichlorobis(2,4,6-trichlorophenyl)urea has been used as a chlorinating agent and transformation takes place rapidly in mild conditions with quantitative yields.