Chemistry Letters, Vol.36, No.8, 1056-1057, 2007
1-(chloromethyl)-4-fluoro-1,4-diazoniabicyclo-[2,2,2]octane bis(tetrafluoroborate) as novel and efficient reagent for the conjugate addition of indoles to alpha,beta-unsaturated ketones
Indoles undergo smooth conjugate addition with alpha,beta-unsaturated ketones in the presence of 10 mol% Selectfluor(TM) under extremely mild conditions to afford the corresponding Michael adducts in high to quantitative yields with 1,4-selectivity.