Chemistry Letters, Vol.36, No.8, 1066-1067, 2007
Nickel-catalyzed carbometalation reactions of [2-(1-propynyl)phenyl]methanol with 1-alkenylmagnesium reagents
Treatment of [2-(1-propynyl)phenyl] methanol with 1-alkenyl-Grignard reagents under nickel catalysis results in carbomagnesiation across the alkynyl part. The 1-alkenylation reaction proceeds in a syn fashion to yield the corresponding 1,3-buta-dienyl- substituted benzyl alcohol.