Geothermal energy is an alternative renewable energy resource that has proven itself technically and economically feasible as a nonpollutant electric power source. The Denizli-Kizildere geothermal energy region is the first major geothermal energy resource project in Turkey, with an estimated potential of 200 MW: The use of the geothermal potential of the region depends on removal of its high boron content, since waste brine is discharged into the nearby Buyuk Menderes River. This article represents a study for removing boron from Kizildere / Turkey geothermal wastewater using the boron selective resin Amberlite IRA-743. The effect of regenerant type and regeneration conditions has been investigated to find the optimal operational conditions for minimizing the regenerant consumption.