It is possible to evaluate the energy demand as well as the parameters related to indoor thermal comfort through building energy simulation tools. Since energy demand for heating and cooling is directly affected by the required level of thermal comfort, the investigation of the mutual relationship between thermal comfort and energy demand (and therefore operating costs) is of the foremost importance both to define the benchmarks for energy service contracts and to calibrate the energy labelling according to European Directive 2002/92/CE. The connection between indoor thermal comfort conditions and energy demand for both heating and cooling has been analyzed in this work with reference to a set of validation tests (office buildings) derived from a European draft standard. Once a range of required acceptable indoor operative temperatures had been fixed in accordance with Fanger's theory (e.g. -0.5 < PMV < -0.5), the effective hourly comfort conditions and the energy consumptions were estimated through dynamic simulations. The same approach was then used to quantify the energy demand when the range of acceptable indoor operative temperatures was fixed in accordance with de Dear's adaptive comfort theory. (c) 2007 Elsevier B.V. All rights reserved.