화학공학소재연구정보센터
홈 로그인 로그아웃 연락처 사이트맵
Macromolecular Research, Vol.16, No.3, 231-237, April, 2008
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Effect of Composition and Synthetic Route on the Microstructure of Biodegradable Diblock Copolymer, Poly(ε-caprolactone-co-L-lactide)-b-Poly(ethylene glycol)
Younjin Min, Seongnam Lee, Jung-Ki Park†, Kuk Young Cho1, †, and Shi-Joon Sung2
  • Department of Chemical & Biomolecular Engineering, Korea Advanced Institute of Science and Technology, Daejeon 305-701, Korea
  • 1Division of Advanced Materials Engineering, Kongju National University, Chungnam 303-717, Korea
  • 2Display and Nano Devices Laboratory, Daegu Gyeongbuk Institute of Science and Technology, Daegu 704-230, Korea
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Biodegradable poly(ε-caprolactone-co-L-lactide)-b-poly(ethylene glycol) (PCLA-b-PEG) copolymers were synthesized via solution polymerization by varying the feed composition of ε-caprolactone (ε-CL) and L-lactide (LLA) (ε-CL: LLA=10:0, 7:3, 5:5, 3:7, 0:10). The feed ratio based on weight is in accordance with the copolymer composition except for the case of ε-CL: LLA=3:7 (C3L7), which was verified by 1H-NMR. Two different approaches were used for the exceptional case, which is an extension of the reaction time or the sequential introduction of the monomer. A copolymer composition of ε-CL: LLA=3:7 could be obtained in either case. The chemical microstructure of PCLA-b-PEG was determined using the 13C-NMR spectra and the effect of the sequential structure on the thermal properties and crystallinity were examined. Despite the same composition ratio of the copolymer, the microstructure can differ according to the reaction conditions.
Keywords:biodegradable;copolymer;microstructure;PEG;sequence distribution
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