나노물질의 인체 및 환경유해성에 관한 위해성평가 방안의 고찰

김미숙; 최경희; 김영훈; 이종협; Mi-Sug Kim; Kyunghee Choi; Younghun Kim; Jongheop Yi

Clean Technology, Vol.13, No.3, 161-172, September, 2007

Export Citation

나노물질의 인체 및 환경유해성에 관한 위해성평가 방안의 고찰

Risk Assessment for Health and Environmental Hazards of Nanomaterials

김미숙, 최경희¹, 김영훈 ², 이종협 ^†

서울대학교 화학생물공학부, 151-742 서울시 관악구 신림동 산 56-1
¹국립환경연구원 화학물질평가부, 404-170 인천시 서구 경서동 종합환경연구단지
²광운대학교 화학공학과, 139-701 서울시 노원구 월계동 447-1

Mi-Sug Kim, Kyunghee Choi¹, Younghun Kim², and Jongheop Yi^†

School of Chemical and Biological Engineering, Seoul National University, San 56-1, Shillim-dong, Kwanak-gu, Seoul 151-742, Korea
¹National Institute of Environmental Research, Environmental Research Complex, Kyungseo-dong, Seo-gu, Incheon 404-170, Korea
²Department of Chemical Engineering, Kwangwoon University, 447-1 Wolgye-dong, Nowong-gu, Seoul 139-701, Korea

E-mail:

초록

청정기술의 발전을 위하여 나노기술이 융합된 새로운 기술의 도입이 필요하다. 최근 개발된 나노입자, 나노튜브 등은 이미 많은 소비재의 원료로 사용되고 있으며, 인체 및 환경에 쉽게 노출될 수 있다. 이러한 나노입자는 작은 크기와 넓은 비표면적 특성으로 인해 기존물질에 비하여 반응성이 높고 인체나 환경에 독성을 나타낼 커다란 잠재성을 가지고 있으며, 이미 많은 연구결과에서 이러한 나노물질이 인체 및 환경 유해성을 유발하는 원인과 결과에 대하여 보고하고 있다. 본 논고에서는 나노기술 기반 청정기술 발전의 방향을 제시하기 위하여 나노물질의 인체 및 환경 유해성에 관한 위험성평가 방안을 검토하고, 나노물질의 잠재적인 위해성을 살펴보고자 한다.

Fusion technology based on the nanotechnology should be introduced to clean technology for the breakthrough advances. Today, nanoparticles, nanotubes and other engineered nanomaterials are already in use in hundreds of everyday consumer products, and these materials are able to move around the human and environmental mediamore readily than larger particles of pollution. Because of their extremely small size and large surface area, nanoparticles are known to be more reactive and toxic than larger particles. Consequently, this feature raised many concerns of significant health, safety and environment. Herein, we reviewed risk assessment for health and environmental hazards of nanomaterials, and then revealed the potential hazardous of nanomaterials.

Keywords:나노물질;전과정평가;위험성평가;나노독성;환경/인체/안전(EHS)

[References]

Kim Y, Yoon CY, Yi J, Polym. Sci. Technol., 15, 173 (2004)
Choi BK, Kim KH, So DS, Yu IJ, Korean Ind. Chem. News, 10(1), 48 (2007)
Kim Y, Yi J, News Inf. Chem. Eng., 23, 338 (2005)
U.S. Environmental Protection Agency, Nanotechology White Paper, EPA 100/-07/001, Feb. (2007)
Maynard AD, Ann. Occup. Hyg., 51, 1 (2007)
Maynard AD, Project on Emerging Nanotechnologies (2006)
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Scientific Committee on Emerging and Newly Identified Health Risks (SCENIHR), The appropriateness of existing methodologies to assess the potential risks associated with engineered and adventitious products of nanotechnologies (2006)
Aitken RJ, Creely KS, Tran CL, Prepared by the Institute of Occupational Medicine for the Health aSafety Executive, North Riccarton, Edinburgh, England (2004)
Lam CW, James JT, McCluskey R, Hunter RL, Toxicol. Sci., 77, 126 (2004)
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[Referenced By]

[Related Articles]

[1] Kim Y, Yoon CY, Yi J, Polym. Sci. Technol., 15, 173 (2004)

[2] Choi BK, Kim KH, So DS, Yu IJ, Korean Ind. Chem. News, 10(1), 48 (2007)

[3] Kim Y, Yi J, News Inf. Chem. Eng., 23, 338 (2005)

[4] U.S. Environmental Protection Agency, Nanotechology White Paper, EPA 100/-07/001, Feb. (2007)

[5] Maynard AD, Ann. Occup. Hyg., 51, 1 (2007)

[6] Maynard AD, Project on Emerging Nanotechnologies (2006)

[7] Maynard AD, Aitken RJ, Butz T, Colvin V, Donaldson K, Oberdrster G, Philbert MA, Ryan J, Seaton A, Stone V, Tinkle SS, Tran L, Walker NJ, Warheit DB, Nature, 444, 267 (2006)

[8] Maynard AD, Kuempel ED, J. Nanopart. Res., 7, 587 (2005)

[9] Miller G, Friends of the Earth (http://nano.foe.org.au) (2006)

[10] Nanoscale Science, Engineering, and Technology Subcommittee, Committee on Technology, National Science and Technology Council, Environmental, Health, and Safety Research Needs for Engineered Nanoscale Materials, the National Nanotechnology Initiative, September (2006)

[11] Scientific Committee on Emerging and Newly Identified Health Risks (SCENIHR), The appropriateness of existing methodologies to assess the potential risks associated with engineered and adventitious products of nanotechnologies (2006)

[12] Aitken RJ, Creely KS, Tran CL, Prepared by the Institute of Occupational Medicine for the Health aSafety Executive, North Riccarton, Edinburgh, England (2004)

[13] Lam CW, James JT, McCluskey R, Hunter RL, Toxicol. Sci., 77, 126 (2004)

[14] Warheit DB, Laurence BR, Reed KL, Roach DH, Reynolds GA, Webb TR, Toxicol. Sci., 77, 117 (2004)

[15] Oberdrster G, Ferin J, Lehnert BF, Environ. Health Perspect., 1002, 173 (1994)

[16] U.S. Environmental Protection Agency, Office of Research and Development. Air Quality Criteria for Particulate Matter. Report Number EPA/600/P-99/002a,bF. October http://cfpub2.epa.gov/ncea/cfm/recordisplay.cfm?deid=87903 (2004)

[17] Oberdrster G, Sharp Z, Atudorei V, Elder A, Gelein R, Kreyling W, Cox C, Inhal. Toxicol., 16, 437 (2004)

[18] Oberdrster G, Oberdrster E, Oberdrster J, Environ. Health Perspect., 113, 823 (2005)

[19] Lecoanet HF, Wiesner MR, Environ. Sci. Technol., 38, 4377 (2004)

[20] Filley RR, Ahn M, Held BW, Blanchette RA, Preprints of Extended Abstracts Presented at the ACS national Meeting, American Chemical Society, Division of Environmental Chemistry 45, 446-450 (2005)

[21] McMurry PH, Atmos. Environ., 34, 1959 (2000)

[22] Oberdrster G, Maynard A, Donaldson K, Castranova V, Fitzpatrick J, Ausman K, Carter J, Karn B, Kreyling W, Lai D, Olin S, Monteiro-Riviere N, Warheit D, Yang H, A report from the ILSI Research Foundation/Risk Science Institute Nanomaterial Toxicity Screening Working Group. Part. Fibre. Toxicol., 2 (2005)

[23] U.S. Environmental Protection Agency, Office of Water. Methodology for Deriving Ambient Water Quality Criteria for the Protection of Human Health (2000) Technical Support Document Volume 2: Development of National Bioaccumulation Factors (2003)

[24] Cheng SH, Cheng J, 229th American Chemical Society Meeting, San Diego, CA March (2005)

[25] Yang L, Watts DJ, Toxicol. Lett., 158, 122 (2005)