화학공학소재연구정보센터
홈 로그인 로그아웃 연락처 사이트맵
Macromolecular Research, Vol.16, No.8, 670-675, December, 2008
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The Effect of Salt and pH on the Phase Transition Behaviors of pH and Temperature-Responsive Poly(N,N-diethylacrylamide-co-methylacrylic acid)
Tonghuan Liu, Jian Fang, Yaping Zhang, and Zhengzhi Zeng†
  • College of Chemistry and Chemical Engineering, Lanzhou University, Lanzhou, P.R. China
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A series of pH and temperature-responsive (N,N-diethylacrylamide-co-methylacrylic acid) copolymers were synthesized by radical copolymerization and characterized by elemental analysis, Fourier-transform infrared (FT-IR), nuclear magnetic resonance (NMR) 1H, 13C and LLS. The effects of salt and pH on the phase transition behaviors of the copolymers were investigated by UV. With increasing NaCl concentration, significant salt effects on their phase transition behaviors were observed. UV spectroscopic studies showed that the phase transition became faster with increasing NaCl concentration. In addition, the phase transition behaviors of copolymers were sensitive to pH. The pH and temperature sensitivity of these copolymers would make an interesting drug delivery system.
Keywords:poly(N,N-diethylacrylamide-co-methylacrylic acid);salt effects pH and temperature sensitivity;phase transition;UV spectroscopic.
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