Study of conventional versus microwave-assisted reactions of 3,4-epoxyalcohols by CeCl3 center dot 7H(2)O: Synthesis of tetrahydrofurans and 1-chloro-3-substituted-2-propanols

Sabitha G; Rao VRS; Sudhakar K; Kumar MR; Reddy EV; Yadav JS

Journal of Molecular Catalysis A-Chemical, Vol.280, No.1-2, 16-19, 2008

DOI10.1016/j.molcata.2007.09.004 Export Citation

Study of conventional versus microwave-assisted reactions of 3,4-epoxyalcohols by CeCl3 center dot 7H(2)O: Synthesis of tetrahydrofurans and 1-chloro-3-substituted-2-propanols

Sabitha G, Rao VRS, Sudhakar K, Kumar MR, Reddy EV, Yadav JS

3,4-Epoxyalcohols undergo regioselective cyclization in the presence of CeCl3 center dot 7H(2)O in refluxing acetonitrile to afford tetrahydrofuran derivatives in good yields. On the other hand epoxyalcohols afforded 1-chloro-3-substituted-2-propanols under microwave irradiation using CeCl3 center dot 7H(2)O supported on SiO2 under solvent-free conditions. (C) 2007 Elsevier B.V All rights reserved.

Keywords:epoxyalcohols;conventional;microwave;tetrahydrofurans;chloro substituted propanols