화학공학소재연구정보센터
Journal of the American Chemical Society, Vol.130, No.8, 2434-2435, 2008
Bronsted acid-catalyzed insertion of aryldiazoacetates to sp(2) Carbon-CHO bond: Facile construction of chiral all-carbon quaternary center
Aryldiazoacetates could be formally inserted into the carbon-carbon bond of the Bronsted acid-activated aromatic and alpha,beta-unsaturated aldehydes. Use of phenylmenthyl esters allowed the asymmetric induction at the inserted all-carbon quaternary carbon center with the excellent stereoselectivities.