The lubrication properties of adsorbed poly(L-lysine)-graft-poly(ethylene glycol) in aqueous buffer solution were studied with the surface forces apparatus. In general, the polymer brushes revealed extremely low friction forces. Two distinct regimes could be identified. In response to lateral shear, the friction forces of intact polymer films at moderate loads were below the detection limit. At high loads, when the films were compressed to about 10% of the original equilibrium film thickness, the friction showed a reversible increase with load. Under certain conditions, film destruction was observed, immediately followed by a dramatic increase in the frictional force and an expansion of the adsorbed brush layer. By the addition of free polymer to the buffer solution, the resistance of the polymer brushes to abrasion was dramatically increased by readsorption of the polymer following friction-induced desorption. This self-healing capacity and the extremely low friction of the adsorbed copolymer films contribute to their excellent properties as lubricant additives for water-based lubrication under boundary conditions.