This investigation examines the use of a high-voltage discharge plasma technology to remove particulate matter from an air stream. Concentrations of the particulate matter were measured at the inlet and the outlet of the discharge plasma with the help of an optical particle counter to determine the particle removal efficiency. The experimental results indicate that the particle removal efficiency of the discharge plasma increased with the discharge voltage. The particle removal efficiency rose as high as 93.1% for 0.3m particles as the discharge voltage was increased to 20kV at an operating frequency of 60Hz. The influence of the operating frequency on the particle removal efficiency was neglected at discharge voltages of 8kV and 10kV when the operating frequencies ranged from 60Hz to 180Hz. Furthermore, the particle removal efficiency increased with the reflected power when the discharge voltage was varied. A non-linear multivariable regression model was fitted to the experimental data. The good fit of the regression model makes it possible to estimate the particle removal efficiency of the high-voltage discharge plasma.