A semi-analytical approach was presented to study the transient heat transfer of a single volatile drop evaporation in an immiscible liquid with bubble nucleation inside the drop. The solution was based on the energy equation included both convection and conduction heat transfer from the continuous liquid to the bubble with the concentric spheres model. The radius of the growing bubble had been found and the effect of Pr number, St number initial radius, initial velocity and ratio of density were examined. The Nu number derived as a function to the drop velocity was derived. The present results compared well with available data.