It is well known that ethanol has less energy per unit volume than gasoline. Differences in engine design and fuel characteristics affect the efficiency with which the chemical energy in gasoline and ethanol is converted into mechanical energy, so that the change in fuel economy may not be a linear function of energy content. This study analyzes the fuel economy tests performed by the US Environmental Protection Agency (EPA) on 2007 model year E85-compliant vehicles and finds that the difference in average fuel economy is not statistically different from the differential in energy content. (C) 2007 Elsevier Ltd. All rights reserved.