Decontamination reactions of sulfur mustard and sat-in were studied on the surface of titania nanotubes and the data were compared with that of bulk titania. Before the reaction studies, titania nanotube samples were made by using hydrothermal method and were characterized by scanning electron microscopy, N-2 BET, X-ray diffractometry, and thermogravimetry. Soon after that, titania nanotube samples were exposed to sulfur mustard and sarin separately at room temperature (30 degrees C) and the reactions were monitored by gas chromatography, whereas the reaction products were characterized by GC-MS. The data explore the role of hydrolysis reactions and surface reactions for the decontamination of both sulfur mustard and sarin. (C) 2008 American Institute of Chemical Engineers AIChE J, 54: 2957-2963, 2008