Selective cell adhesion on an ion implanted poly(bisphenol A carbonate) film

Ho-Je Kwon; Chan-Hee Jung; In-Tae Hwang; Young-Chang Nho; Jae-Hak Choi

Journal of Industrial and Engineering Chemistry, Vol.15, No.5, 703-706, September, 2009

DOI10.1016/j.jiec.2009.09.049 Export Citation

Selective cell adhesion on an ion implanted poly(bisphenol A carbonate) film

Ho-Je Kwon, Chan-Hee Jung, In-Tae Hwang, Young-Chang Nho , and Jae-Hak Choi^†

Advanced Radiation Technology Institute, Korea Atomic Energy Research Institute, Jeongeup-si, Jeollabuk-do 580-185, Republic of Korea

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Conventional ion implantation has been shown to modify the surface properties of polymers such as their hardness, conductivity, and biocompatibility. In this study, poly(bisphenol A carbonate) (PC) films were implanted by Ar+ ions with an energy level of 100 keV in order to improve their biocompatibility. The results of the surface analyses revealed an increasing intensity of the functional groups on the ion implanted PC surfaces such as OH, C=O, and C-O after implantation, which contributed to an improvement of their hydrophilicity. The in vitro cell culture test revealed that the HaCaT cells were selectively adhered to the ion implanted regions of the PC.

Keywords:Poly(bisphenol A carbonate);Ion implantation;Surface modification;Cell adhesion

[References]

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San J, Zhu B, Liu J, Liu Z, Dong C, Zhang Q, Surf. Coat. Technol., 138, 242 (2001)
Kwon HJ, Jung CH, Kim DK, Lim YM, Kim HK, Nho YC, Choi JH, J. Korean Phys. Soc., 52, 819 (2008)
Adams MR, Garton A, Polym. Degrad. Stab., 42, 145 (1993)
Sharma R, Holcomb E, Trigwell S, Mazumder M, J. Electrostat., 65, 269 (2007)
Wang Y, Jin Y, Zhu Z, Liu C, Sun Y, Wang Z, Hou M, Chen X, Zhang C, Liu J, Li B, Nucl. Instrum. Methods B, 164, 420 (2000)

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[3] You ES, Jang HS, Ahn WS, Kang MI, Jun MG, Kim YC, Chun HJ, J. Ind. Eng. Chem., 13(2), 219 (2007)

[4] Jung H, Kwak B, Yang HS, Tae G, Kim JS, Shin K, Colloids Surf. A, 313, 562 (2008)

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[6] Nathawat R, Kumar A, Kulshrestha V, Singh M, Ganesan V, Phase DM, Vijay YK, Appl. Surf. Sci., 253(14), 5985 (2007)

[7] Welle A, J. Biomater. Sci., 15, 357 (2004)

[8] Frerichs H, Stricker J, Wesner DA, Kreutz EW, Appl. Surf. Sci., 86, 405 (1995)

[9] Seidel C, Kopf H, Gotsmann B, Vieth T, Fuchs H, Reihs K, Appl. Surf. Sci., 150, 19 (1999)

[10] Moczo J, Pukanszky B, J. Ind. Eng. Chem., 14(5), 535 (2008)

[11] Bhattacharya RS, Surf. Coat. Technol., 103, 151 (1998)

[12] Shin YJ, Yang DH, Oh MH, Yoon YS, Shin JS, J. Ind. Eng. Chem., 15(2), 238 (2009)

[13] Guzman L, Miotello A, Voltolini E, Adami M, Thin Solid Films, 377, 760 (2000)

[14] San J, Zhu B, Liu J, Liu Z, Dong C, Zhang Q, Surf. Coat. Technol., 138, 242 (2001)

[15] Kwon HJ, Jung CH, Kim DK, Lim YM, Kim HK, Nho YC, Choi JH, J. Korean Phys. Soc., 52, 819 (2008)

[16] Adams MR, Garton A, Polym. Degrad. Stab., 42, 145 (1993)

[17] Sharma R, Holcomb E, Trigwell S, Mazumder M, J. Electrostat., 65, 269 (2007)

[18] Wang Y, Jin Y, Zhu Z, Liu C, Sun Y, Wang Z, Hou M, Chen X, Zhang C, Liu J, Li B, Nucl. Instrum. Methods B, 164, 420 (2000)