Chemistry Letters, Vol.38, No.7, 664-665, 2009
alpha-Amidobenzylation of Aryl and Alkenyl Halides via Palladium-catalyzed Suzuki-Miyaura Coupling with alpha-(Acylamino)benzylboronic Esters
The Suzuki-Miyaura coupling of alpha-(acetylatnino)benzyl-boronic esters with aryl and alkenyl halides has been achieved using a Pd/P(t-Bu)(3) catalyst with KF and H2O in 1,4-dioxane, giving a-substituted benzylamines in high yields.