In this study, three semipredictive activity coefficient models: Wilson, non-random-two liquid model (NRTL), and universal quasi-chemical model (UNIQUAC), have been used for modeling vapor-liquid equilibrium properties of ternary mixtures that include substances found in alcoholic distillation processes of wine and musts. In particular, vapor-liquid equilibrium in ternary mixtures containing water+ethanol+congener has been modeled using parameters obtained from binary and ternary mixture data. The congeners are substances that although present in very low concentrations, of the order of part per million, are important enological parameters. The results given by these different models have been compared with literature data and conclusions about the accuracy of the models studied are drawn, recommending the best models for correlating and predicting phase equilibrium properties of this type of mixtures.