Electrodialysis of manganese (II) containing solutions has been studied. It was shown that Mn (II) cations themselves do not render any negative impact on the ion-exchange membranes. These ions are highly movable within the cationite membrane phase and may be easily removed during the electrodialysis desalination up to the maximum permissible concentration allowed for the potable water. The reason of possible impairment of the electrochemical characteristics of membranes during the electrodialysis of the Mn (II) containing solutions is scaling on the surface of the anion-exchange membranes in brine side. This is observed under severe concentration polarization conditions. The techniques to avoid deposition of the poorly soluble manganese compounds on the surface of the anionic membranes in brine side are proposed.