Wastewater treatment performance of the combined process of upflow anaerobic sludge blanket (UASB) reactor and sequencing batch reactor (SBR) was studied. An experimental study has been conducted investigating the performance of the system under different operating conditions. Three experimental runs were considered. The retention time in the UASB was changed from 4 h to 3 11 and the aeration time in the SBR cycle varied from 2 to 5, and then to 9 h. The results indicated that the average percentage removal for the three runs for COD, BOD and TSS was 94%, 97% and 98% respectively. Complete nitrification of ammonia was achieved after 5 h aeration in the SBR. The water quality of the treated wastewater resulted from the integrated system at different operating conditions complied with the local standards regulating wastewater discharge into agriculture drains. The main advantage of the proposed treatment system is the minimization of investment and operational costs as compared to the use of the SBR systems alone. The implementation of the anaerobic pretreatment leads to reduction of the plant area, sludge production and oxygen requirement 40%, 58%and 62% respectively.