A good quality pre-treatment process is instrumental to the successful operation of a seawater reverse osmosis (SWRO) plant. The compounds that are susceptible to foul the reverse osmosis (RO) membranes are inorganic suspended solids, sand, oil, clays, bacteria, and dissolved organic matters. In order to prevent the fouling, a pre-treatment of the raw water needs to be conducted. The pre-treatment technologies to prevent membrane fouling and to extend the lifetime of the RO membrane are commonly grouped into two categories, conventional and non-conventional. Both of these treatments are currently applied in SWRO plants in the world. The pre-treatment system applied is highly site specific and depending on the type of the feed water. This paper reviews the recent representative researches that are related to SWRO antifouling strategies and answers the most crucial questions about design and operating parameters of SWRO and its pre-treatment process. Also the economic evaluation of the SWRO system in regards to antifouling strategies' experience is discussed. (C) 2009 Elsevier B.V. All rights reserved.