An extended Gebhart-Block model for large space buildings is proposed in this paper, which is used to predict the vertical temperature distribution of hybrid ventilation. Natural ventilation coupled with air-conditioning is described with a mathematical model. The indoor thermal environment formed by the air-conditioning and the natural ventilation can also be conducted for the potential analysis and optimal use of the natural ventilation. Experiments were carried out in an atrium building in Shanghai Research Institute of Building Sciences. This paper describes aforementioned model, and it is found that the calculation results implying this model agree well with the measurement data. (C) 2009 Elsevier B.V. All rights reserved.