Double skin facade can be defined as a building facade covering one or several stories with multiple skins. The skins may be air tight or ventilated. With sophisticated study and design, buildings constructed with double skin facade can have better thermal performance than the conventional single skin facade. This paper reports the findings on the energy performance of double skin facade applied to a typical office building under the climatic condition in Hong Kong. An experimental setup was established and the measured data were used to verify the theoretical model developed via the EnergyPlus simulation program. The validated model was then used to evaluate the energy performance of double skin facade with various configurations including glazing type (clear, absorptive or reflective glass), glazing position (inner or outer pane) and glazing layers (single or double glazing material). The results indicate that a double skin facade system with single clear glazing as the inner pane and double reflective glazing as the outer pane can provide an annual saving of around 26% in building cooling energy, as compared to a conventional single skin facade with single absorptive glazing. However, the long payback period of 81 years makes the double skin facade system economically infeasible. Support and motivation are needed from the local government in order to foster successful and widespread application of the double skin facade system in buildings. (C) 2009 Elsevier B.V. All rights reserved.