A new one-dimensional heterogeneous model has been developed to describe the three-phase mass transfer in the presence of one or more particles in the diffusion path of the absorbed component in the liquid boundary layer at the gas-liquid interface. The diffusion of the absorbed component, from the gas-liquid interface into the bulk phase, perpendicular to the interface, occurs alternately through continuous phase and dispersed one in the multi-composite medium of the boundary layer. Due to the spherical particle surface, the diffusion distance between particles and inside of the particles continuously changes along the surface. Its effect was also taken into account by averaging the absorption rate integrating it over the full circle area of the gas-liquid interface corresponding to the size of particles located in the diffusion path. This average value of the mass transfer rate was applied for the heterogeneous portion of the gas-liquid interface in the case of uniformly distributed particles in the boundary layer. In the case of absorption into slurry containing fine solid particles with their irregular distribution in the boundary layer, the particles were modelled as cylindrical ones of identical volume. The mass transport through the heterogeneous medium has been solved using the very general film-penetration theory. The effect of mass transfer- and first-order reaction kinetic parameters as well as the particle size has been discussed. Then, the simulated data were verified by previous experimental studies. The models presented make it possible to describe the absorption rate in the presence of particles with optional size, or of optional number, in the boundary layer perpendicular to the gas-liquid interface.