Both porosity and permeability constitute the major parameters in core analysis. In this study, the variation of these two parameters along a sandstone core sample was investigated during formation damage. A water-based drilling fluid was dynamically circulated through the core sample for three different time intervals of 15 min, 45 min, and 60 min at 100 psi circulation pressure. The core sample was analyzed using x-ray digital radiography by sectional image approach. The differences in the porous media due to fines migration by drilling fluid were examined. Digital image subtraction method was applied by using an in-house simulator developed to run with MATLAB to determine porosity. The experimental results obtained by dynamic circulation and x-ray imaging were compared with the results obtained by using a numerical fines migration simulator. Consistent matches between the experimental and numerical results were observed indicating that porosity and permeability impairments with distance can be described accurately.