A two-zone fluidized bed reactor (TZFBR) is employed for propane dehydrogenation over a Pt-Sn-K/gamma-Al2O3 catalyst. This type of reactor constitutes an alternative to the use of two separate reactors with solid circulation between them or of a single reactor with periodic operation and allows continuous operation with in situ catalyst regeneration. The effect of the main TZFBR operating variables is studied and the reactor performance compared with results obtained in other works using Pt-Sn based catalysts, showing that a steady state is reached with similar selectivity to that. reported in the literature for other reactors which suffer the problem of catalyst deactivation.