In this paper, we study the potential of entrainer in reactive distillation involving high boiling reactants to decrease the reactive Stage temperature and for separation of one of the products to enhance the conversion. Esterification of ethylene glycol with acetic acid in the presence of Amberlyst 36 with 1,2-dichloro ethane (EDC), as ail entrainer, is chosen as the model reaction. The effect of different parameters on selectivity of diacetate of ethylene glycol (DAEG) in entrainer based reactive distillation (EBRD) has been studied both through experiments and simulations. The results show that, by using entrainer, it is possible to obtain close to 100% selectivity toward diester even with a stoichiometric mole ratio, which is otherwise not possible in a conventional reactor.