In Part 1, a numerical model for coupled heat and moisture transfer in a run-around heat and moisture exchanger with a liquid desiccant coupling fluid is developed. The numerical model is two dimensional, transient and is formulated using the finite difference method with an implicit time discretization. The results from the numerical model for the case of only heat transfer for a single heat exchanger are compared to an available analytical solution and good agreement is obtained. For the simultaneous heat and moisture transfer in the run-around membrane energy exchanger (RAMEE), a comparison between numerical model results and experimental measurements obtained from laboratory testing for both sensible and latent effectiveness showed satisfactory agreement at different operating conditions. Part 11 of this paper applies the model for a range of initial conditions [32]. (C) 2009 Elsevier Ltd. All rights reserved.