Li2.06Nb0.18Ti0.76O3 powder has been successfully prepared at low temperatures via a facile and manageable, activated pretreatment on the inert raw Nb2O5. It is demonstrated that with triethanolamine, citric acid, and hydrogen peroxide, this simple pretreatment process could activate Nb2O5 efficiently. Pure Li2TiO3 solid solution phase was thus obtained by calcining the mixture of the activated Nb2O5, LiOH. H2O, and Ti(C4H9O)(4) at temperatures as low as 650 degrees C, which is about 200 degrees C lower than that of the traditional solid-state method. To the best of our knowledge, this temperature is the lowest one for preparing Li2TiO3 solid solution. Additionally, the phase transformation and the morphology of the final powder are also discussed.