Journal of the American Chemical Society, Vol.130, No.44, 14398-14398, 2008
A Diazirine-Based Nucleoside Analogue for Efficient DNA Interstrand Photocross-Linking
A diazirine-based nucleoside analogue (DBN) efficiently forms DNA interstand cross-linking under near-UV irradiation. This new base analogue may find broad applications in biotechnology and phototherapy.