Journal of the American Chemical Society, Vol.131, No.6, 2092-2092, 2009
The Effect of Alkynyl Groups on Torquoselectivity. Highly Stereoselective Olefination of Alkynyl Ketones with Ynolates
We have shown the first experimental evidence of the alkynyl substituent effect on torquoselectivity and succeeded in effecting the highly torquoselective olefination of alkynyl ketones to provide functionalized tetrasubstituted olefins.